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Up to 43% of patients may partially recover their vision

If nausea persists beyond this period or is severe, patients should contact their healthcare provider for assessment and potential dose adjustment

These applications represent off-label use, and the evidence is primarily from small trials and observational studies

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However, three patients did develop serological changes (low complement and/or positive anti-dsDNA) at 6-10 months without corresponding clinical symptoms

In addition to heterogeneity, potential sources of bias must be considered, particularly in observational studies assessing treatment persistence and real-world effectiveness