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Increases in alkaline phosphatase, without other evidence of hepatic abnormality, also has been reported

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J Endocrinol 219:5968 Mieczkowska A, Mansur S, Bouvard B, Flatt PR, Thorens B, Irwin N, Chappard D, Mabilleau G (2015) Double incretin receptor knock-out (DIRKO) mice present with alterations of trabecular and cortical micromorphology and bone strength