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Description
Pharmacological inhibitors of SLC7A11, such as sulfasalazine (107) and cisplatin (108), act through distinct mechanisms to disrupt redox homeostasis
An J, Zhou Y, Zhang M, et al

Long-term conclusions rely on extrapolation Marie Spreckley, obesity researcher and public health nutritionist at the University of Cambridge in England, who was not involved in the study, cautioned that the papers long-term conclusions rely on modeled projections, rather than observed data, as the follow-up period for stopping treatment with newer medicines is limited to about 12 months

What are the expected benefits of using Semaglutide GLP-1 for weight management
The 12 mg group lost an average of 24.2% body weight at 48 weeks versus 22.8% in the 8 mg group, a difference of 1.4 percentage points

Menopausal status did not meaningfully alter treatment response, as seen here: What we know about hormone therapy and weight-loss response Menopausal hormone therapy is not indicated for weight loss
