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While inconvenient, its much lower than the diarrhea reported in up to 30% of people taking prescription injectables, see Wegovy Medication Guide, which also lists 44% rate of nausea

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Persistent headaches may indicate the need for dose adjustment, additional interventions, or investigation of alternative causes

doi: 10.1016/j.ejphar.2008.12.056

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The glucagon pathway in particular produces effects, including thermogenesis and hepatic lipid mobilization, that no prior GLP-1 or GLP-1/GIP compound prepared the body for