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Senate Republicans repeatedly said they want to curb spending, both in the lead up to the June 30 budget deadline and during the public debates throughout the impasse

To assess the impact of follow-up duration, Cox models were stratified by 6 months, 12 months, and 24 months

Sub-2mg microdose draws are off-label and have not been studied in trials

Missed doses can impact effectiveness

Common exclusions across TRIUMPH trials include a personal or family history of medullary thyroid carcinoma or MEN syndrome type 2, prior pancreatitis, a body-weight change greater than 5 kg in the 90 days before screening, and use of weight-loss medications within 90 days

Nat Med 30 , 18301831 (2024)