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1 Researchers acknowledged the genetic effect on weight loss was relatively small but said the findings lay the foundation for precision medicine approaches to obesity treatment by providing direct evidence that variation in drug-target genes contributes to differences in how patients respond

Because youre less hungry and feel full longer, you eat less, and that leads to weight loss

Decreased appetite This is technically the intended therapeutic effect, but some people experience appetite suppression so profound it becomes problematic

Introduction Incretins are hormones secreted by intestinal cells in response to ingested nutrients that play a role in the regulation of glucose homeostasis
