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We are bound to learn much about their side effects in the coming years

The drug received approval from both the US FDA and the European Union in 2022 for the treatment of type 2 diabetes, demonstrating signicant glucose-lowering and weight-loss efects in multiple clinical trials

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*A study found GLP-1 RAs to be associated with a significant 12-14% reduction in major adverse cardiovascular events (Source) I was nervous going into it because I never tried medication to help with weight loss

Do you have a history of heart failure or recent cardiac events

Table 1 illustrates that the most significant obstacles to progress across these systems have not been a lack of physiological relevance, but unresolved pharmacologic, technological, or conceptual challenges