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The guidelines are expected to be published soon, following a public consultation held in September

On the other hand, GIP-green-fluoresent-protein (GFP)-knock-in (GIP gfp/+ ) mice, in which GIP secretion is attenuated to half that of WT mice, exhibit no decrease in bone mass compared to wild-type mice, with no significant difference in blood glucose or insulin levels during OGTT after 8 weeks of HFD, although slight glucose intolerance was observed under a normal diet [18, 100]

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The group that exercised and received liraglutide averaged similar weight loss to the group that just received liraglutide, though the combination group was more successful in preserving bone health, the researchers said