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14,15 Using the formula for comparing two means, with a two-sided = 0.05 and power = 80%: the minimum required sample size to detect a difference in HbA1c was 39 patients per group (78 total) and the minimum required sample size to detect a difference in BMI was 48 patients per group (96 total)

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1 Usually, clinically apparent liver function abnormalities lead to the diagnosis after the age of 40 when the accumulated iron causes damage as the result of hemosiderosis
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