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Jon: Balancing these two things is actually really difficult, as exercise tends to make people hungry, which then can make it hard to stay in a calorie deficit

574 As a negative regulator in cardiac hypertrophy, SIRT3 protects the heart by inhibiting intracellular ROS

The best option depends on your providers recommendation

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Many patients find morning dosing psychologically reinforcing because they observe reduced hunger immediately before their largest meals, creating visible cause-and-effect motivation
