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Although extensive misuse is not yet well-documented, these medicationslike other weight-loss drugs such as stimulants, topiramate, and orlistatmay contribute to the development or worsening of eating disorder psychopathology (Bartel et al., 2024)

Suspected adverse reactions should be reported via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
Human studies examining circulating METRNL levels have produced heterogeneous results, reflecting differences in metabolic state, physical activity, and assay methodology
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2004;287(6):E1209-1215

In AD brains, the TCA cycle is disrupted [36]
