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Followed for 12 months
58: 13421349 [DOI] [PMC free article] [PubMed] [Google Scholar] 107.Nauck MA, Heimesaat MM, Behle K, et al

In the context of prolonged systemic administration, NMDA receptor antagonists, such as memantine and MK-801 (also known as dizocilpine), induce anorexia and weight loss in rodents 9,10,11

Despite continued weight loss on average in both responders and nonresponders, no statistically significant difference in weight loss was observed between the final weight recording periods (6 months to 9 months)

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