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Every side effect profile, every weight loss outcome, every blood sugar reduction number in the clinical data assumes weekly administration

Note that some restrictions apply

Check our tirzepatide refrigeration guide for complete storage instructions

A 29-gauge needle is slightly thicker, which means the medication flows through it more easily, but you feel it slightly more during insertion

You can continue taking the medication for as long as: It remains medically appropriate You tolerate it well Your prescriber approves continued use Frequently asked questions Is Mounjaro a lifelong medication

While most GLP-1 shortages resolved in early 2025, regional supply issues can still arise