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Purpose-built for physicians Trial Scorecard: ACHIEVE-1 The ACHIEVE-1 trial evaluated orforglipron, a novel nonpeptide, small molecule oral GLP-1, for glycemic control and weight loss in patients with type 2 diabetes

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This medication works by mimicking the naturally occurring GLP-1 hormone, which stimulates insulin secretion, suppresses glucagon release, and slows gastric emptying

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