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Chem Senses (2013) 38(1):6775

GLP-1 receptor agonists are not prescribed solely for cholesterol management , but certain patient groups may derive particular benefit from their lipid-modifying effects alongside their primary indications

Adipocyte-specific Gipr ablation protects mice from HFD-induced insulin resistance and hepatic steatosis, potentially by reducing circulating levels of pro-inflammatory cytokines (68)

Although tachyphylaxis to this effect may occur with long-acting GLP-1 receptor agonists, GLP-1-associated slowing of gastric emptying does not appear to be responsible for the nausea and vomiting often reported with the use of GLP-1 receptor agonist treatment

Matsuda M, DeFronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp

[DOI] [PubMed] [Google Scholar] 112.Blher M, Aras M, Aronne LJ, et al