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Amini MR, Sheikhhossein F, Talebyan A, Bazshahi E, Djafari F, Hekmatdoost A

Report data indicate that current GLP-1 users are now snacking, dining out, and drinking alcohol less frequently than before starting these medications

Notably, the observed variability in efficacy between agents, particularly in the early phases of treatment, emphasizes the importance of individualized therapeutic strategies, tailored to specific clinical goals, baseline metabolic profiles, and patient preferences

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Next, we examine how GLP-1 RAs impact each of the twelve proposed hallmarks of aging

A variant associated with stronger GLP1R signaling predisposition does not guarantee superior weight loss on semaglutide or tirzepatide