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Overall, the available data support a favorable efficacy versus safety balance for gut-hormone hormone receptor analogues in the treatment of these subjects

Semaglutide works by mimicking a natural gut hormone that tells your brain when you're full, helping you eat less and maintain weight loss over time

Withdrawal symptoms can occur if you immediately stop taking semaglutide

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Given these considerations, the therapeutic approach in older patients with T2D is complex, particularly in those who have functional dependence, frailty, dementia, or who are at end-of-life