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3, 7 They protect cell connections

Finally, GLP-1s slow down digestion, changing the way a person's body turns food into energy

GLP-1 agonists including semaglutide slow gastric emptying, which can intensify alcohol effects and increase nausea risk

Weight loss continued accumulating through the entire study period, with many patients still losing weight at the 72-week mark

Properties of these agents are summarized in Table 1

Dulaglutide (Trulicity, Eli Lilly) consists of two fused GLP-1 analogues, with a glycine substitution at position 2, a glutamic acid substitution at position 20 and a glycine at position 30, which protect against DPP-IV degradation [19, 32]