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Rotating between sites serves two purposes: it prevents lipodystrophy (localized fat changes at repeated injection points) and potentially affects absorption rates

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In addition, since the first evidence of a beneficial effect of GLP-1RAs in BAD treatment was not available until 2019, we notice that the prescriptions of GLP-1RAs up until this year were made for other indications than BAD in contrast to bile acid sequestrants

10.1016/j.bbi.2020.10.014 98 SunH.ShuJ.TangJ.LiY.QiuJ.DingZ.et al (2024)

Expecting weight loss to persist after stopping treatment makes as much sense as expecting blood pressure to stay low after stopping blood pressure medication