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The mechanistic explanation: GLP-1 receptors are expressed in brain regions involved in reward processing specifically the ventral tegmental area (VTA) and nucleus accumbens (NAc), both central to the reinforcing effects of alcohol, food, and other substances

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Diabet Med 2008;25:570577

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Nausea 12-33%, diarrhea 12-21%, vomiting 5-13%

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Benefits of Post-Weight Loss Surgeries Improved Body Contour: Surgery after massive weight loss removes excess skin and fat, resulting in a more toned and defined body shape

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These changes correlate with weight loss magnitude, particularly reduction in visceral adiposity and neck circumference

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