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84 The study also demonstrated that the drug decreased hepatic lipid accumulation and inhibited pro-inflammatory and profibrotic gene expression

Limitations While we demonstrate a statistically significant (moderately robust) association between GLP-1 therapy and NAION, notable limitations exist

These larger, longer-duration studies will provide the comprehensive safety and efficacy data needed for FDA review

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The other may be creating a flatter curve with less intensity but more consistency
