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While semaglutide was initially approved primarily for diabetes management, it has increasingly been prescribed off-label by weight-loss specialists due to its remarkable results in clinical trials

Unlike subcutaneous fat (the fat you can pinch under your skin), visceral fat is metabolically hyperactive

2016 Jan;4(1):2-3

The effects of weight loss were observed upon daily liraglutide injection (Mora and Johnson, 2017), oral administration of liraglutide (3 mg) (Manigault and Thurston, 2016), and subcutaneous treatment of liraglutide for 20 weeks (1.2 to 3 mg) (Onoviran et al., 2019)

Merchenthaler I, Lane M, Shughrue P

Bear case: EVOKE shows no statistically significant difference on CDR-SB at two years and there is no Alzheimers label indication