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This is particularly critical before surgical procedures, as tirzepatide's effect on gastric emptying may necessitate adjusting the timing of the last dose prior to anesthesia to reduce aspiration risk

Kim KS, Park JS, Choi HJ

This represents a fundamental shift in how these medications are prescribed

The MHRA assesses the drug's quality, safety, and efficacy

Binding results indicated that M2 and M4 bound to the human GLP-1 receptor with 1030-fold higher affinity than semaglutide (Table 2)
