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During pregnancy, Lp(a) values increase ~2-fold and return to baseline levels after delivery [87], hence some available studies have indicated an increased risk of pregnancy complications, including preeclampsia, low birth weight or preterm delivery, and some guidelines recommend monitoring Lp(a) levels during pregnancy [88]

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It also affects more women than men, suggesting a link with sex hormones

These approaches are not environmentally friendly, due to the number of reactions, and the need to use chiral starting materials or chiral auxiliaries (Meyer and Robins, 2005

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