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Weight loss without a strategy can lead not only to the reduction of fat but also to the quiet erosion of muscle

There hasnt been a medical innovation thats been this impactful, really, since the advent of statins, Nunn said in a phone interview, referring to the cholesterol-lowering drugs that premiered in 1987 and were prescribed to an estimated 92 million Americans in 2018 and 2019
This suppresses production of pro-inflammatory cytokines including TNF-alpha, IL-1beta, and IL-6 (the same IL-6 that paradoxically stimulates GLP-1 production in a feedback loop)
Increased intestinal permeability ("leaky gut") allows bacterial lipopolysaccharides (LPS) to enter the bloodstream, triggering systemic inflammation that impairs insulin signaling

Keep a food and mood journal to recognize patterns between emotions and eating behaviors

Science 286 , 711715 (1999)
