glp 1 agonist contraindications GLP-1 Agonists GLP-1 Receptor Agonists: antidiabetic and

DPP-4 is a member of the serine peptidase/prolyl oligo-peptidase gene family, which includes the membrane-bound peptidases, fibroblast activation protein (FAP)/seprase

The incretin-related therapies dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) not only improve glycaemic control with a low risk of hypoglycaemia but can also have beneficial non-glycaemic effects such as avoidance of weight gain, reduced blood pressure and improvements in beta-cell function and cardiovascular risk biomarkers 1 3

doi:10.1016/j.neurobiolaging.2020.04.003 110

Combining them would increase side effect risk without adding meaningful efficacy

funded this work

SoftwareX 12 , 1925 (2015)