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Despite being quite treatable, these infections are a considerable health concern because they can cause serious illness or even be fatal

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105 An analysis done on eight cohort studies concluded that metformin was observed to be related to reduced cancer incidence as compared to sulfonylurea monotherapy in T2D patients

This scenario leads to an increase in oxidative stress (OS), which is related to mitochondrial dysfunction, accumulations of protein and oxidated lipids, and an impairment of the antioxidant system [64,65,66,67,68,69,70]

Specifically, ferulic acid has been shown to bind GLP-1 and inhibit dipeptidyl peptidase-4 (DPP-4), the enzyme responsible for its rapid inactivation, thereby extending the hormones biological activity [20]